Source: http://moviesblog.mtv.com/2013/01/30/scarlett-johansson-sex-scenes-joseph-gordon-levitt/
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Thursday, January 31, 2013
Scarlett Johansson Love Scenes Were 'Not A Sexy Enterprise' For Joseph Gordon-Levitt
One of the first things that may pop into your head while watching Joseph Gordon-Levitt's performance in his directorial debut and Sundance darling "Don Jon's Addiction" is "Jersey Shore." But when MTV News' Josh Horowitz asked about the connection to the recently concluded reality show, the "Dark Knight Rises" star pleaded ignorance. "I had never [...]
Wednesday, January 30, 2013
Tiffany Coyne Expecting First Child
The Let's Make a Deal model, 30, and her husband Chris are expecting a baby together, her rep tells PEOPLE exclusively.
Source: http://feeds.celebritybabies.com/~r/celebrity-babies/~3/2z4y_23_a-M/
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You are 'When' You Eat, New Study Finds
Jan 29, 2013 7:00am
When you eat matters, a Spanish study found. (Image credit: Getty Images)
In dieting, like comedy, timing is everything. That?s the conclusion of a new Spanish study that suggests that when you eat might be just as important as what you eat.
During the first few weeks of the 20-week study, run by researchers from Brigham and Women?s Hospital in collaboration with Tufts University and the University of Murcia, all 420 subjects lost weight at about the same rate. But starting around week five, weight loss for dieters who ate their main meal after 3 p.m. began to stall and remained sluggish for the duration of the study. In the end, they lost 22 percent less weight than dieters who ate the bulk of their calories earlier in the day.
The results left researchers scratching their heads. All the subjects ate and burned off about the same number of calories. They all followed a Mediterranean-style diet consisting of lean proteins, fruits and vegetables and healthy fats such as olive oil, and consumed about 40 percent of their daily calories at lunch. They all slept approximately the same number of hours each night and, when tested, their appetite and hunger hormone levels were comparable. Even their genetics were similar.
The late-in-the-day eaters did tend to be breakfast-skippers, and they showed a higher level of insulin resistance. But according to the researchers, these differences alone didn?t explain the variability in weight loss between late and early eaters ? and neither of these factors was correlated with the amount of an individual?s weight loss.
The researchers? best guess is that that eating later in the day messes with the body?s internal clock system, known as circadian rhythms, and this might somehow have an adverse effect on metabolism.
Frank Sheer, one of the study?s coauthors and an assistant professor of medicine at Harvard Medical School, explained it this way:
?The circadian system is made up of a master clock in the brain and peripheral clocks in most cells throughout the body. Normally, the master clock synchronizes all peripheral clocks, similar to the conductor of an orchestra. When meal timing is abnormal this leads to de-synchronization between these different clocks, resulting in a cacophony.?
Over the years, many a popular fad diet has sung the virtues of early-in-the-day eating patterns. But David Just, co-director of Cornell University?s Center for Behavioral Economics in Child Nutrition, said the results of this latest study notwithstanding, such advice may not apply to Americans.
?Spaniards tend to eat their largest meal midday,? he said. ?Starting toward the end of the eighteenth century, as more people in this country began taking factory jobs that didn?t allow them to pop home for lunch, Americans began shifting their main meal toward the end of the day, which is how most of us still tend to manage our eating.?
Just said he suspects that Americans who eat less in the first part of the day simply eat more later on to compensate. His own studies with school-age children show that kids who eat an early lunch tend to skip breakfast and have large afternoon snacks. He?s also found that kids who eat a late lunch often enjoy a light afternoon snack but make up the calories by having an enormous dinner. The kids who ate the fewest calories in his studies?regularly?had their lunch right around noon.
Sheer also said he believed it?s too soon to relate his study?s outcomes to the American lifestyle. But he does think the timing of eating could be an important part of weight loss.
?These new findings may help in developing new strategies to further optimize weight-loss therapies in the battle against obesity,? he said.
SHOWS: Good Morning America
Source: http://abcnews.go.com/blogs/health/2013/01/29/you-are-when-you-eat-new-study-finds/
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Remains of the Day: The Nexus 4 Is Finally Available Again on Google Play
The Nexus 4 is no longer sold out on Google Play, Microsoft's Surface Pro comes with less space than you'd expect, the iPad gets super-sized, and the US government issues a security warning.
- Google Once Again Selling the Nexus 4 in the US, Canada, Germany, More Locations to Come Soon (Update) The perpetually out-of-stock Nexus 4 is finally available again in the Google Play Store. Customers in the US, Canada, and Germany can now order the smartphone in both 8GB and 16GB models. Expect a shipping time of one to two weeks, although actual wait times have been reported to be much shorter. Best Buy also has the phone available, provided you plan to sign up with T-Mobile. [The Verge]
- Microsoft's 64GB Surface Pro Will Only Have 23GB Usable Storage If you're looking to get a Surface Pro when it launches next week, there's one major caveat to keep in mind: the tablet will come with a lot of it's free space already used. This will leave those who buy the 64 GB model with only 23 GB of free space, and 83 GB free on the 128 GB model. However, some of this can be reclaimed due to a portion of that already-used space set aside for recovery. By creating a backup bootable USB device you'll be able to delete the recovery partition and free up a bit more space. [The Verge]
- Apple Increases iPad with Retina Display to 128GB Today Apple announced that it will be selling a 128 GB version of the iPad with Retina display. This version is otherwise identical to the last model that went on sale last fall, and will sell for $929 with WiFi and Cellular or $799 for WiFi only. They'll be available starting Tuesday, February 5th. [Apple]
- U.S. Government Warns of Hack Threat to Network Gear The US Department of Homeland Security's Computer Emergency Readiness Team issued a warning today urging everyone to disable Universal Plug and Play (UPnP) protocol due to new findings from security company Rapid7. To avoid being exploited, you should disable UPnP once you have your network set up?it won't have any negative effect on performance. [Reuters]
- YouTube Set to Introduce Paid Subscriptions This Spring YouTube will soon experiment with paid subscriptions. Likely to be tested on one of it's more popular networks like Machinima or Fullscreen, the paid channels will cost somewhere between $1 and $5 a month. YouTube is also considering charging for content libraries and access to live events. [AdAage]
- 500px Photography App Returns to App Store With 17+ Rating After 'Pornography' Removal After being pulled from the App Store last week over nude photos, photography browsing app 500px is now back online. During its absence, the app's rating was changed to 17+, and a "report" feature has been added for offensive photos. Search has also been tweaked to make it harder for offensive pictures to show up when using suggestive queries. [The Verge]
- Amazon Elastic Transcoder (beta) Amazon's newest web service is a video transcoder based in the cloud. Called Amazon Elastic Controller, the beta release will let you transcode up to 20 minutes of content per month for free, allowing you to prep your videos for whatever output format best suits your needs for web or mobile playback.
Photo by photastic (Shutterstock), a2bb5s (Shutterstock), and Feng Yu (Shutterstock).
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Law pits small businesses against Nova Scotia Liquor Corp. - Need ...
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HALIFAX ? A Nova Scotia law dictating where hobbyists can make their own wine and beer has uncorked a torrent of condemnation among observers who say the provincial government is picking on the little guy.
The province?s Crown liquor corporation is seeking a court order to stop the owners of Wine Kitz Halifax and Water ?n? Wine in New Glasgow from producing wine and beer in their stores.
The Nova Scotia Liquor Corp. says it?s merely upholding provincial law, which allows people to brew at home.
But Richard Dunn, a senior policy analyst with the Canadian Federation of Independent Business, said the law is anti-competitive and threatens the underpinnings of a free market.
?It?s turf protection for the liquor corporation,? he said. ?And it comes at the expense of private enterprise.?
Regulatory changes introduced by the provincial government in 2011 give the liquor corporation the authority to seek a court order to prevent businesses from allowing customers to use brew kits on their premises.
The owners of Wine Kitz Halifax and Water ?n? Wine in New Glasgow are contesting the injunction. The matter is scheduled to return to Nova Scotia Supreme Court next month.
According to the Nova Scotia government, in-store wine and beer production is permitted in five provinces: Prince Edward Island, New Brunswick, Ontario, Saskatchewan and British Columbia.
Nova Scotia?s distinction as the only Maritime province to ban the practice has unleashed frustration and disbelief in newspaper columns and letters to the editor.
?Cannot Finance Minister Maureen MacDonald see what is clearly unacceptable police-state harassment by NSLC of small business owners?? David Young of Lunenburg, N.S., wrote in a letter to the Halifax Chronicle Herald.
Another reader, Michael Pierce of Pictou, N.S., denounced the liquor corporation?s actions as ?Gestapo-like tactics.?
?The mom and pop stores which allow the average person to brew beer and wine at a modest cost should not only be lauded, but promoted,? he wrote.
Dunn said he?s not surprised by the public outcry.
?When you create that imbalance or unlevel playing field, it puts people?s backs up,? he said in an interview from Moncton, N.B.
MacDonald, the minister responsible for the Liquor Control Act, declined repeated requests for comment as the matter is before the courts.
Terri Mosher, a spokeswoman for Nova Scotia Liquor, said the corporation was upholding the interests of law-abiding businesses that wanted action taken against so-called U-vints and U-brews.
?For us, it really comes down to enforcing the act,? she said.
Mosher said the court action was launched after the corporation hired investigators to pose as customers and make wine on-site last year. She declined to comment on any ongoing undercover efforts.
She said one of the corporation?s main objections to in-store brewing was safety, not potential revenue loss.
?They?re manufacturing unregulated product in a retail environment,? she said.
Wine Kitz owner Ross Harrington defended his product, saying the corporation is simply flaunting its power.
He said the NDP government?s reputation among entrepreneurs is being strained as a result.
?I think the public outcry is obvious,? said Harrington. ?The optics for the government are bad.?
Liberal Opposition Leader Stephen McNeil said his party has repeatedly introduced bills in the legislature to protect businesses that offer in-store brewing, but to no avail.
?This is a heavy-handed approach being used by a Crown corporation to stamp out the entrepreneurial spirit of these Nova Scotians,? McNeil said.
Progressive Conservative Leader Jamie Baillie has called for an overhaul of the province?s liquor laws, starting with in-store brewing ? or ?regulation gone crazy,? as he put it.
?With all the issues our province has, I can?t believe the NDP has decided that squashing small independent business people and hobbyists ? is an important priority,? Baillie said.
Dunn said Nova Scotia has lost the momentum it gained in recent years in cutting red tape for small businesses. He said the U-vint and U-brew ?nonsense? is only compounding the province?s economic woes.
The federation recently gave the province a grade of D for its efforts to slash red tape in an annual report card.
Dunn said heaping the bureaucratic burden on small enterprises could scare off potential entrepreneurs if it continues to happen.
?You?re not building the confidence of the business community by coming out with these barriers,? he said.
?If it becomes a pattern ? you?re going to have people thinking twice about either relocating to Nova Scotia or perhaps trying to start up a business of their own.?
Source: http://www2.macleans.ca/2013/01/29/law-pits-small-businesses-against-nova-scotia-liquor-corp/
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Tuesday, January 29, 2013
Toyota back on top as global auto sales champ
1 hr.
Toyota has officially reclaimed its global sales crown, the maker confirming it produced 9.75 million vehicles in 2012.
That was slightly ahead of a preliminary tally Toyota forecast as the year came to a close and locks it in first place ahead of General Motors, which sold 9.29 million vehicles.? Volkswagen, at 9.1 million, came in third for 2012.
Toyota?s sales were slightly lower than the company had projected earlier in the year, the shortfall reflecting the ongoing dispute between Japan and China over a chain of small, uninhabited islands both nations claim.?
In customary fashion, Toyota officials downplayed the sales results. ?Rather than going after numbers, we hope to make fine products, one by one, to keep out customers satisfied. The numbers are just a result of our policy. And our policy will continue unchanged,? Toyota spokeswoman Shino Yamada told the Associated Press.?
The Detroit Bureau:?US Auto Sales Surging as New Year Gets Underway
Nonetheless, it marked a significant comeback for the Japanese giant which first captured the global sales crown in 2008, displacing GM after seven decades as the sales leader. The U.S. maker plunged into bankruptcy the following year, recovering only with the assistance of a massive government loan.
With production back to normal, Toyota saw its sales in the home Japanese market surge 35% in 2012 while overseas sales jumped 23%.? Adding additional models to the ?family,? the Prius line firmed up its position as the world?s best-selling hybrid nameplate.Toyota briefly fell to third in the global chase in 2011, the maker suffering significant production cuts in the wake of Japan?s March earthquake and tsunami. It didn?t fully restore its worldwide production network to normal operations until the end of the year.
But not everything went as well as expected ? notably in China where Toyota was just one of many Japanese businesses to suffer as the dispute over the Senkuko Islands ? which the Chinese call the Daioyu ? flared up. A Toyota dealership was torched and mobs destroyed many of the maker?s products. Sales fell by roughly half in the early weeks of the dispute though they have begun to recover more recently.?
The Detroit Bureau:?Mazda betting on alliances with Toyota, Fiat
Toyota did have some other issues, notably a surge of safety-related problems including additional recalls related to the maker?s unintended acceleration issue. In all, Toyota recalled more vehicles than any other maker in the American market in 2012, and it ended the year by agreeing to an estimated $1.2 billion settlement related to the unintended acceleration issue. Even so, most analysts say the maker?s reputation escaped with relatively little damage.
Toyota is forecasting another increase in sales for 2013, hoping to reach a record 9.91 million. That is still short of an earlier projection of at least 10 million, however.
General Motors officials have not yet set out their own forecast and that could depend on the strength of the ongoing U.S. recovery. Earlier this month, Chairman and CEO Dan Akerson said the maker expected sales in the States to reach somewhere between 15.0 million and 15.5 million for 2013.?
The Detroit Bureau:?Toyota Settles First of 100s of Wrongful Death, Injury Lawsuits
The wild card is Volkswagen, the aggressive German maker laying out plans to snatch the sales ground by the time it wraps up its current, 10-year growth plan in 2016.? The weakness of the home European market could delay that strategy, though VW hopes to offset that by stressing China, Latin America and the recovering U.S. market where it was one of the fastest-growing brands in 2012
.
Copyright 2013 The Detroit Bureau
Source: http://www.nbcnews.com/business/toyota-back-top-global-auto-sales-champ-1C8137475
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92% Skyfall
All Critics (284) | Top Critics (46) | Fresh (261) | Rotten (23)
It's been a long time since I enjoyed a Bond movie so much.
'Quantum of Solace,' was a dour, dire letdown. This picture's a substantial bounce back, and easily the best Craig Bond picture. Emotional depth and all.
Sam Mendes' 'Skyfall': sleek, slithery, sensual
The cool accomplishment of Skyfall, 23rd in the Broccoli franchise, is that it seems a necessary, rather than mandatory, addition to the year's popular culture.
Among the most ambitious imaginings of Bond to date: dark, supple, and punctuated with moments of unanticipated visual brilliance.
Mendes' approach to action is classical and elegant - no manic editing and blurry unintelligible images here - but what makes the movie special is the attention he pays his actors.
One of the ten best films of 2012.
The film serves as a trip back to the beginning of the 50-year-old cinematic legend and the promise of a golden future with Craig in the role of 007.
What propels this grisly chapter is the characters' keen sense of agency.
Skyfall epitomizes what a Bond movie should be, and its director, for once, justifiably deserves much of the credit.
Skyfall isn't quite a throwback to the absurd thrills of the 007 films of old, but it does inject some fun back into the franchise.
As the saying goes, you've got to shake 22 Bond films, before the 23rd is stirred to perfection. Without a doubt, this is the best James Bond movie.
James Bond looks broken and weary, an embodiment of a traditional model of international spydom, the one premised on national borders, white-Western-wealthy entitlements, and excessive consumptions of alcohol, cars, and women.
I have no compulsion whatsoever in declaring Skyfall, in terms of cinematography, the best looking Bond film ever ... Action movies simply don't look like this - but ... this is no ordinary action movie.
Sentimental touches underscore the fun and frivolity of Bond's past while relishing the brutal landscape of the modern day super-spy.
This makes the list of truly great 007 films alongside the list of Goldfinger, Thunderball, Live And Let Die, Licence To Kill, Goldeneye and Casino Royale.
Worlds collide in this near-brilliant, meticulously refined 21st-century redefinition of James Bond.
Sam Mendes has done a magnificent job, creating both a relevant and timeless entry into the Bond canon, while deftly adding homages to the series' past.
...tough and grim but still spry ... feels like something of a rearguard action in the case of the British Empire.
Sometimes the old ways are the best. This is a theme and repeated line running throughout the new James Bond film Skyfall and never has it been more true.
Skyfall does what all of the best franchise entries do: it makes you want to see the next one immediately. Consider me (physically) shaken and (emotionally) stirred.
Not the best Bond movie ever but a very good one; a little darker but still unsettled as to what type overall it wants to be.
Too often this martini is sloppy, not smooth.
This is one of the 50-year-old series' most exciting and commandingly compelling entries. Yes, James Bond is back to being James Bond.
Seen against the ineffectual backdrop of 2008's Quantum of Solace, this is a return to form but it doesn't exceed Craig's impressive debut as Bond in 2006's Casino Royale.
Source: http://www.rottentomatoes.com/m/skyfall/
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Monday, January 28, 2013
Tips To Consider While Starting An Online Business ? Weblink India ...
For small-time entrepreneurs, starting an online business makes a lot of sense, especially with many buyers indulging in online shopping today.? Online stores are fast emerging as the preferred option among the new age buyers, who prefer shopping while sitting in the comfort of their homes. To make a success out of the online business venture, one can consider the many tips suggested below.
Tips To Consider While Starting An Online Business
- Before starting an online business, it is essential to decide upon a target audience. Questions like ? who are the target group, what are their needs, etc. are relevant to a business & should be duly considered.
- A well designed website is a very important aspect of online business. Since for an online business the website is going to be the point of contact between the sellers & customers, it is essential that the website is an appealing one & makes a positive impression on the visitors? minds.? A well designed website with good content can also attract word-of-mouth publicity for the business which will lead to increased visibility and more sales.
- An SEO optimized website is a must, if one wants to attract more of web traffic. There are other ways to increase the flow of visitors to a website too, like listing the business on Online Business Directories. This is a foolproof way of providing more exposure to the online business.
- The special offers, discounts and deals should be displayed in a prominent manner on the website, so that visitors can easily spot the offers & respond if they want to. For this, providing up to date contact information (of the company) on the website is also essential. Another important point that needs to be ensured is to keep the navigation part (while browsing the website) easy and hassle-free for the visitors.
- Building contacts is very essential for the online business in the long run. For this, an online business can make use of networking tools like blogging, twitter, Facebook, etc. to build up a network of useful contacts.
The best thing about Online Business is that it is easy to measure the results & to determine whether the strategies being implemented are having the desired effect or not. Implementing the tips mentioned above will ensure that the Online Business turns out to be a successful venture.
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Source: http://blogs.weblinkindia.net/2013/01/28/tips-to-consider-while-starting-an-online-business/
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Justin Bieber On Selena Gomez Breakup: 'There's So Many Rumors'
Bieber opens up to Billboard about split, ahead of Tuesday's Believe Acoustic.
By Jocelyn Vena
Justin Bieber and Selena Gomez
Photo: Albert L. Ortega/ Getty Images
Source: http://www.mtv.com/news/articles/1700893/justin-bieber-selena-gomez-breakup-comment.jhtml
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African leaders meet in Ethiopia amid Mali crisis
ADDIS ABABA, Ethiopia (AP) ? African leaders met in the Ethiopian capital Sunday for talks dominated by the conflict in Mali as well as lingering territorial issues between the two Sudans.
The African Union says it will deploy a force in Mali, where French troops are helping the Malian army to push back Islamist extremists whose rebellion threatens to divide the West African nation.
United Nations Secretary-General Ban Ki-moon is attending the two-day summit in Addis Ababa, where Ethiopian Prime Minister Hailemariam Desalegn took over from President Yayi Boni of Benin as chairperson of the African Union.
With Mali at the top of the agenda, African leaders hope they can make quick progress in deploying a substantial number of African troops there. As the African leaders met, French special forces fighting alongside Malian troops were pushing farther north into the Malian desert in an offensive against al Qaida-linked Islamists who took control of northern Mali more than nine months ago.
Africa's economic boom is threatened by violent conflicts across the continent, African Union officials said at the summit.
"While we are proud of the progress made in expanding and consolidating peace and security on the continent, we also acknowledge that much still needs to be done to resolve ongoing, renewed and new conflict situations in a number of countries," said African Union Commission Chairperson Nkosazana Dlamini-Zuma.
Dlamini-Zuma said the Peace and Security Council of the African Union will report to the summit on efforts to resolve conflicts in countries ranging from Mali to Madagascar.
The Peace and Security Council of the African Union said in a statement Saturday that it wanted "the early operationalization of the African Standby Force" in Mali. The council also said it fully supports Mali President Dioncounda Traore but urged him to put in place a roadmap to free and fair elections. It also said the African Union is committed to preserving the unity of Mali and would "spare no efforts" to safeguard the country's territorial integrity.
A number of African countries have pledged to send troops to Mali, and on Tuesday the African Union will hold a conference of donors with hopes that money will be raised for the Mali force. The Peace and Security Council of the African Union urged member states to "seize the opportunity of the donors' conference ... to meaningfully contribute toward the mobilization of the necessary resources."
The council also urged the international community to contribute generously to the Mali force.
Meanwhile, the leaders of Sudan and South Sudan met at the summit in Addis Ababa, although African Union officials said they did not expect them to make much headway. South Sudan President Salva Kiir and Sudan President Omar al-Bashir earlier this month agreed to "the unconditional and speedy" implementation of deals they had reached back in September. But a subsequent meeting of the two countries' negotiating teams that should have outlined timetable for the deal's implementation ended in disagreement.
Ban urged the two Sudans to resume direct talks and spoke of the "dangerous humanitarian situation in Southern Kordofan and Blue Nile states."
"In Sudan and South Sudan the parties have taken positive steps to resolve outstanding issues," Ban said. "But they should make more progress in meeting their agreements."
Mediators led by former South African leader Thabo Mbeki have until July to push the two sides to agree on the status of the disputed Abyei region as well as other contested border areas.
Source: http://news.yahoo.com/african-leaders-meet-ethiopia-amid-mali-crisis-100222090.html
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Sunday, January 27, 2013
Video: White House focuses on immigration, guns
Sorry, Readability was unable to parse this page for content.
Source: http://video.msnbc.msn.com/nightly-news/50608977/
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Ren? Girard gets new honor ? from the King of Spain, no less | The ...
An immortel in 2005
I was visiting with Ren? and Martha Girard last night at their Stanford home. He was a bit under the weather with an oncoming cold, and Martha brewed a Chinese tea for all three of us.? In the domestic setting, they didn?t whisper a word of the latest international news.? But here it is this morning:
Professor Emeritus Ren? Girard will be granted the Order of Isabella the Catholic, Commander by Number, by the Spanish head of state, H.M. King Juan Carlos. Girard is receiving the decoration ?for his outstanding work, during the past decades, in the fields of philosophy and anthropology.? ? The Order of Isabella the Catholic is a Spanish civil order bestowed upon both Spanish citizens and foreigners in recognition of services that benefit the country.
What service has he rendered Spain?? Recall the role of Don Quixote in his landmark Deceit, Desire and the Novel.
A statement from the cultural advisors to King Juan Carlos points to Girard?s ?profound attachment? to ?Spanish culture as a whole? as reason for the award. Girard has repeatedly said that the works of Miguel de Cervantes, one of Spain?s greatest writers, have been crucial to him when it came to elaborating his theories.
Merci.
The article notes that the mimetic theory is ?arguably? his most famous theory.? Okay, I?ll argue.? At least a little.? Having spent hours poring over the clippings in the Girard archives at the Biblioth?que Nationale de France, the biggest file of news clippings is easily Violence and the Sacred.? When I speak to Europeans ? such as Mario Biagini, or Tomas Venclova ? they say that Violence and the Sacred is the book that had a powerful impact on their thinking and their lives.
That?s the book that made an apparent (but only apparent) U-turn from literary theory to anthropology, sociology, and the social sciences.? He began to theorize about the origins of violence, and the role of the scapegoat in unifying societies.? He lost a few fans, no doubt, who wanted the shoemaker to stick to his last ? but that?s the book that moved him into another sphere, making him one of the greatest thinkers of the last century.
The Consul General of Spain in San Francisco, Jorge Montealegre Buire, delivered the award to the immortel of the Acad?mie Fran?aise in a private ceremony with his family today.? I hope it went well.
There is always a takeaway when I visit Girard.? This time I took away ? his cold.? It may be a quieter weekend than I?d planned.
Tags: Jorge Montealegre Buire, King Juan Carlos, Ren? Girard
Source: https://bookhaven.stanford.edu/2013/01/rene-girard-gets-new-honor-from-the-king-of-spain-no-less/
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#SciAmBlogs Friday - Glassfrogs, Age of Miracles, bad smells, Rotifer in Motion, chemophobia, Geodesign and more.
About the Author: Bora Zivkovic is the Blog Editor at Scientific American, chronobiologist, biology teacher, organizer of ScienceOnline conferences and editor of Open Laboratory anthologies of best science writing on the Web. Follow on Twitter @boraz.More??
The views expressed are those of the author and are not necessarily those of Scientific American.
Source: http://rss.sciam.com/click.phdo?i=f237aa8901fac5f214c78172e7891aea
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Saturday, January 26, 2013
PM Aviation Contributor Matt Molnar Passes Away at 33
Sad news from the PM family. Matt Molnar, an aviation contributor and co-owner of the website NYCAviation.com, died suddenly last night in Brooklyn, N.Y., at age 33.
Most recently, Matt reported on the Boeing 787 controversy for popularmechanics.com. In years past he brought great stories about new jets, airliner safety, and other flight issues to our site. Prior to that he worked in our office as online producer.
Matt is survived by his fiance Gina and brother Steven.
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Economist: Euro crisis could erupt again this year
DAVOS, Switzerland (AP) ? Is the euro crisis over? A leading U.S. economist says not by a long shot.
Barry Eichengreen warns that the debt crisis that has shaken Europe to its core could easily erupt again this year unless European leaders move faster to solve their problems.
While European governments and markets have been breathing easier in recent months after years of turmoil, it's no time for complacency, said Eichengreen, who has chronicled the Great Depression and explored the consequences of a breakup of the euro currency used by 17 nations.
"Nothing has been resolved in the eurozone, where markets have swung from undue pessimism to undue optimism," Eichengreen told The Associated Press in an interview at the World Economic Forum in Davos, Switzerland. "They said all the right things last year ... and they've been backtracking ever since."
He warns that the crisis over too much debt burdening governments and banks in the 17-country currency group "is going to heat up again in 2013."
He urged eurozone leaders follow up on its proposals to steady its banking system and keep failed banks from adding to government debt through expensive bailouts.
European leaders in Davos this week are seeking to reassure investors and corporate leaders that the continent is on the mend after its punishing debt crises.
Heavily indebted countries such as Spain and Italy faced alarmingly high borrowing costs on bond markets last year, as investors wondered whether they would be able to keep paying their debts. Those bond market rates fell after key steps by European leaders. One was the European Central Bank's offer to purchase bonds issued by indebted countries if they promise to reduce their deficits. Another was a proposal to set up a so-called banking union that would keep failed banks from bankrupting any one country by transferring the supervision of bank behavior and finances to a single, central EU supervisor at the ECB.
The banking union decision was key. Meanwhile, Europe is in a recession that is putting added pressure on government finances.
"Europeans will be shocked out of their complacency, I think, soon enough," Eichengreen said. "There will be a relapse to the greater volatility of the first half of last year."
"None of the underlying problems have been solved. There is no economic growth in Europe. Germany itself is on the verge of recession. The banking union doesn't exist. There's less consensus on completing it than we thought last year, so the markets are going to lose patience at some point and the crisis will be back. "
Eichengreen, a professor at the University of California, Berkeley, studied the possibility of a eurozone breakup long before the crisis that started in late 2009 forced other people to consider what was once unthinkable. He concluded that leaving the euro would be disastrously expensive and cause widespread chaos for any country that tries it.
Political leaders are aware of those high costs, which means a country such as debt-strapped Greece leaving the eurozone "is off the table for the moment," he said.
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Jojoba Oil- The Perfect Solution to Any Skin Problem! | Gnet Health ...
It isn?t often that you come across a skin product that can be used on any skin-type, relieving dry patches and calming oily patches with equal effectiveness. What about a skin product that you can also use on your hair, that will moisturize to a lustrous finish, and deal easily with those stubborn greasy build-ups? Meet the wonderful, versatile and restoring power of Jojoba oil!
What is Jojoba Oil?
Jojoba oil is actually a liquid wax that is derived from the jojoba plant, a wax-rich shrub that is native to desert areas of North America.
Jojoba oil is used extensively in cosmetics and is an extremely popular alternative to petroleum jelly, since it is derived from plants rather than from fossil fuels. Its popularity has risen all the more since it has become unfashionable, and often illegal to use whale blubber in soaps and cosmetic products.
As well as being used extensively as a natural ingredient in beauty products like lotions, shampoos and moisturisers, the oil is also used widely in its pure state, since it has properties very similar to the sebum produced in our own skin- this makes it a wonderful moisturiser ,that is non-greasy and easily absorbed. Jojoba oil also has fantastic fungicide properties.
Let?s have a closer look at the uses of Jojoba, and its potential benefits to our daily beauty routine!
Jojoba: The Ultimate Moisturiser?
What makes jojoba so great is its similarity to the oil that our own skin produces, called sebum. This means that our skin knows exactly how to deal with it, absorbing it quickly and easily, and using it to create a powerful barrier against moisture-loss, as well as against allergens and irritants like dust and pollution.
For those pesky dry patches, this is just the thing to soften and restore your skin to a healthy condition. All of this makes jojoba oil a great treatment if you suffer from skin conditions that are caused by a lack of moisture, like eczema. Not only that, but jojoba oil has anti-inflammatory properties, which will take down the redness caused by dryness, or by skin conditions like rosacea.
If you?re reading this and wishing there was a moisturizer just as good for oily skin, then we have the answer for you, and that answer is?.jojoba oil!
Yes that?s right- it goes against all instincts to put oil on an already oily surface, but jojoba oil mimics our skin?s sebum so closely, that it is thought to act like a signal to our pores to not produce anymore oil of it?s own.
Jojoba oil is becoming an effective and popular treatment for acne. Need a bit more convincing? Have a look at what these people think:
I?ve Always Had Spotty Skin
I never leave reviews but I was so pleased with this stuff that I had to.
I can?t say I?ve ever had acne but always ALWAYS had spotty skin, large pores, dry patches etc etc Every night I would wash my face and rush to put on moisturiser before my face cracked. Now I can leave me face to re-balance itself at night without clogging with any creams
And this cleared it up within a couple of days;
- fill sink a little warm water
- Add couple of drops of Oil and swish around
- Splash on your face pressing it in rather than rubbing ? do that a good few times; repeat several times
- Get a muslin cloth (or clean flannel!) And run it under a very, very cold tap.
- Press the cloth over you ? forehead ? bridge of nose ? cheeks ? chin. If it starts to warm, run under cold tap.
After the first few days you may still need a little moisturiser to make you feel better! However after 2-3 days bare skin all the way for a good kip!
? JB ?
(www.amazon.co.uk) ?
If You Have Acne, This is Great!
If you have acne this is a great product. I mix this with everything an also use this in my night time skin routine. After cleansing with Garnier pure active wash & toner i use jojoba oil, a 5 pence piece amount to moisturize my face at night. My skin is smooth and soft the next day and I?ve noticed my complexion is a lot more even now. Also I have oily combo skin and I?ve noticed that my skin doesn?t get greasy any more towards the afternoon.
? Love Sagas ?
(www.amazon.co.uk) ?
And this isn?t just one for the ladies; For those men that dread that morning shave and end it with a face of raw skin and sensitive hair follicles, jojoba oil may well be your new best friend. Rubbed over the whole beard area, the oil serves to soften stubble and provide a smooth surface for the razor to run over, reducing friction and the chance of snagging or grazing. Plus, your face will stay soft and moisturized for the rest of the day!
Jojoba Oil For Your Hair:
If you?ve ever fought to get rid of that awful build-up of grease and hair product, but can?t seem to shift it with your regular shampoo, then try a bit of pure jojoba oil, massaged directly into your scalp, and we are confident that you?ll notice the difference!
This is because jojoba is great at breaking down oils, cleaning hair follicles and removing dirt; and when used on the scalp it can have that same wonderful oil-regulating effect that it has on greasy skin. So this could be just what you need if you find your hair getting greasy very quickly, as it will regulate sebum production in your scalp, and get you back on a balanced footing in no time at all.
As for the rest of your hair, the jojoba will moisturize it incredibly quickly, since it will soak up the oil as easily as it soaks up your natural sebum. Simply apply it to hair and massage in prior to your shampoo, and enjoy the results!
Are there any Side-Effects to Using Jojoba Oil?
There are only a couple of things to take into consideration when you are using jojoba oil. Firstly, make sure that it is jojoba oil that you are using! Look for 100% pure brands, which are cold-pressed, for the best quality oil. Jojoba oil that is contaminated with other vegetable oils will not be as effective, and may worsen any skin problems you have.
And be sparing! A little goes a long way with jojoba oil, so see how your skin reacts to it, and once it is no longer absorbing the oil then stop applying it. You shouldn?t be left with any greasy residue after using jojoba oil- if you are, then you are using too much., and you won?t be helping your skin.
What the Press Says:
Times of India: (Click article for full size)
Related posts:
Source: http://www.gnet.org/jojoba-oil-the-perfect-solution-to-any-skin-problem/
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Friday, January 25, 2013
Board Games | Shoba Narayan
It is a simple game involving five pebbles of medium size. We called it Anchangal (five stones), but it could well have been played with 10 or 11 stones. It took a little practice and there was scope for improvement. You started by throwing one pebble up in the air and picked up another pebble while it fell. Then you graduated to picking up two pebbles while one was in the air; then three and more. You could throw two pebbles up in the air and attempt to pick up an equal number. It took concentration and hand-eye coordination. It absorbed my friends and me for hours when we were children.
Most often, we played it on hot summer afternoons at my grandmother?s house when the adults slept. But the game, which required little more than a flat surface and five stones, could be played in railway compartments, waiting rooms and balconies. We spent a lot of time foraging for the right-sized pebbles and cowrie shells to add to the game?s toolkit.
An excellent website called?Traditionalgames.in?has a video clip showing how the game is played. Other websites devoted to traditional games conjecture that this simple game spread through the Silk Route to Turkey, Spain and Korea, where it is called Besh Dash, Payana and Gonggi, respectively. Having played it for years, I can attest that it does indeed improve eyesight, concentration and motor skills. In fact, I have restarted playing it now because it is?like doodling?a great stress buster and a harbinger of the elusive muse that only surfaces when you are distracted or in a Zen state of mind.India is home to many of the world?s most ancient games, including Pachisi, which was exported to England, recreated into Ludo, and then returned to India to be played by many a child during the summer holidays. ?Nowadays, Indian children play Ludo completely oblivious to the fact that it is a monstrous decomposition of their own fantastic board game,? said Irving Finkel in?Time?magazine in 2008. Finkel, who works at The British Museum, is an authority on board games, including the Royal Game of Ur, widely considered to be the oldest board game in existence.
India?s contribution to board games is extensive, as documented by Finkel, R. Vasantha and V. Balambal, all of whom are experts on the topic. In speeches and reports, Vasantha describes some of the more interesting indoor games such as Mancala, Tigers and Goats, and Single Track. Balambal, who specializes in the indoor games of Tamil Nadu, is mentioned in Levingston?s Board Game Blog (http://boardgameblog.wordpress.com/) along with Nirbed Ray and Amitabha Ghosh, who have edited a hard-to-find book called?Sedentary Games of India, published by The Asiatic Society, Kolkata. Anyone interested in how board games were created, spread and played should read these blogs.My favourite game used to be Snakes and Ladders, but now I find that it too is a monstrous translation of the original Indian version. In 1860, a Harvard dropout named Milton Bradley created a board game called The Checkered Game of Life or Life, as it was popularly called. In the game, the players simulated their travels through life with jobs, children, education and hurdles. The Game of Life was arguably America?s first parlour game, and certainly its most popular.
Bradley may have popularized the game but he borrowed its ideas from many an ancient culture, including India, where this checkerboard and the accompanying game were called by various names:jnana chaupar,?gyan chaupar, and?parama pada sopanam?(steps to the highest place). Originating around 1200, this game had squares called houses and four players whose movements were dictated by the throw of dice. It was thought to be excellent preparation for the victories and vicissitudes of life with all its glorious vagaries. Players took on personas, and if they were virtuous, they climbed the ladder. Fortunes changed with the throw of a dice, which brought along winds of change. If you were unlucky, you were swallowed by a snake and had to go down several steps. But don?t fear, was the underlying message: After every snake came a ladder; after falling down, you would go up.
The main thing was to maintain equanimity because the game had no clear winner. All that mattered was to reach the top of the board and everyone would. The original game didn?t have the ?winner-take-all? strategy that became part of its Western avatar. Rather, it was heavily imbued with the Hindu notion of?maya?or illusion that translated into ladders of success and snakes of failure, both of which were part of the game of life.
Traditional Indian games are being revived through companies such as Chennai-based Kreeda, Mysore-based Kreedaa Kaushalya and others. I became interested in ancient Indian board games after listening to Jill Lepore?s excellent lecture on ?The Meaning of Life?. Say, you are an elementary schoolteacher and you want to teach your students the meaning of life with all its ups and downs, what do you do? Perhaps you should play Snakes and Ladders with them, not the modern version but the original Indian version.
Shoba Narayan is looking to buy a Gyan Chaupar board. Write to her at thegoodlife@livemint.com
Source: http://shobanarayan.com/2013/01/25/board-games/
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AT&T lost $3.9 billion in Q4 2012, earned $7.3 billion profit for the year
American telecommunications giant AT&T announced its Q4 2012 financial results this afternoon, which reflect $3.9 billion in losses for Ma Bell's final fiscal quarter of last year. However, the company's also posting "record smartphone sales" of 10.2 million last quarter -- "the most by any US carrier," it claims. As it's Q4, the results for the full year are also in; AT&T revealed $7.3 billion in net income across the entirety of 2012. That's what we'd call a marked change from last year's losses.
In terms of phones, AT&T activated 8.6 million new iPhone customers (16 percent of which were totally new to the company), up 1 million over 2011's Q4 and nearly double that of Q3 2012. No specific number is given on Android sign-ups, but AT&T's calling it the "best-ever sales quarter for Android smartphones" -- when those 8.6 million iPhones are subtracted from the overall Q4 2012 sales of phones (10 million), it's not looking so good for non-Apple built devices. On the U-verse front, the latest lifetime subscriber numbers reflect 8 million TV and high-speed internet users, with 192K joining in Q4 2012.
Operating revenues just barely exceeded those of 2011, reaching $127.4 billion, offset by $114.4 billion in expenses (down $3 billion over 2011). Customer numbers also grew in 2012, by a healthy 1.086 million people, the vast majority of which are contract customers (approximately 70 percent). Needless to say, things seem to have gone pretty okay for AT&T in 2012, despite a rocky final quarter. Not too bad for the least loved mobile carrier in the US.
Update: This post originally reflected $3.9 billion in profit for Q4 2012, when it should've reflected losses. Please excuse our error!
Filed under: Cellphones, Handhelds, Tablets, Wireless, HD, Mobile, AT&T
Source: http://feeds.engadget.com/~r/weblogsinc/engadget/~3/lwiSrfGbsRY/
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Thursday, January 24, 2013
When and if it might make sense to outsource Human Resources 4 ...
This is my fourth installment in a series in which I discuss issues and considerations that would go into determining whether Human Resources functions and processes should be retained in-house, or whether they should be outsourced to third party providers ? and if so for which services (see HR and Personnel, postings 134 and loosely following for Parts 1-3.)
I said at the end of Part 3 that I would turn to discuss the issues of in-house versus outsourced Human Resources from the employee and manager perspective in this posting and I begin doing so by grouping all employees ? with and without management responsibilities in their job descriptions and responsibilities, into one group of constituent stakeholders. And I bring their experience and needs into focus with an example that generically would be familiar to most any reader of this posting: calling a phone system customer help or support desk and particularly during off-hours.
I am writing explicitly about HR support and its availability and effectiveness, but cite a more widely experienced working example that would include help desk support in general, as outsourced HR help desk and phone based support carries with it essentially all of the same strengths and weaknesses as are found when consumers call for retail business or manufacturer customer support. All of these are third party provided from the caller perspective and both can involve connecting with people who are very distantly located and who are primarily if not exclusively reading from scripts, for any actual answers provided. And they can be badly written and inflexible scripts and read through the barriers of language and culture differences.
I have a lot of colleagues who I really respect professionally in places like Mumbai and Chennai, India (formally known as Bombay and Madras, respectively) and in businesses that provide third party help desk support. They and their competitors, collectively comprising a minor growth industry, have come to play an increasingly significant and pervasive element to the help desk and customer support system and for a tremendous range of commercial enterprises. And I add that some of my own best experiences in reaching out for help desk support as a consumer and business professional have come from distantly located professionals who spoke expertly and with concern for the customer. But I have to add that some of my most difficult and frustrating experiences have come from having to deal with poorly trained help desk and support personnel, reading from badly drafted scripts who did not have anyone to escalate a call to that they could not handle. And it is the bad experiences that we remember and talk about.
When an employee seeks help from a distant third party Human Resources center, chances at that they are calling about an issue or a problem that is very significant to them. This holds with equal force for lower level employees and for senior managers, or for anyone in-between. And when a business brings onboard a third party HR provider that comes to be seen from shared negative stories, as being more of a problem itself than an answer to problems, that raises questions about the competence of the business? leaders in general. If they cannot run their own business for its internal functioning and in ways that are supportive of the people who work there, what can they do right?
? This creates problems for rank and file employees and for their managers as they have to deal with members of their teams who are distracted and upset.
? This can negatively impact upon overall business productivity.
? This type of challenge can and does negatively impact on staff retention and particularly for employees who are most difficult to replace with special combinations of skills and experience ? that other businesses would be eager to hire away. Bad workplace experiences can in effect help lead your most valuable employees toward the exit.
? And I have to add that when communications disconnects and related problems stemming from poorly outsourced HR cause breakdowns in addressing issues such as discrimination or harassment challenges, that leads to very high level risks for the business as a whole and with potential consequences that can become very severe and very quickly.
? And once a Human Resources capability that was in-house is outsourced and dismantled, it can be difficult and expensive to recreate it back in-house again if outsourcing this area of business functionality has not worked out. Outsourcing is not irrevocable or nonreversible but doing so carries with it at least a short term costs-barrier that would have to be accepted and dealt with and that can be significantly large.
I write of this as a set of due diligence and risk identification and remediation issues, and outsourcing or keeping in-house an area of business functionality is always at least in significant part exactly that. From an employee perspective, outsourcing HR can be risky and with risks that outweigh benefits if it is not done effectively or if the wrong HR functions are shipped out.
I am going to turn next to consider Human Resources in the multinational corporation setting, and where centralization or dispersed localization, or some combination thereof would make more sense ? think of this as a discussion of where ?in-house outsourcing? might make sense, where that is how a business? employees would see this. Meanwhile, you can find this and related postings at HR and Personnel and also at Outsourcing and Globalization.
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Earth in Action: Italian earthquake verdict exposes rifts between science and society
By Alexandra Witze
Web edition: January 23, 2013
Sometimes a little shake-up is exactly what scientists need to make a major breakthrough. Other times it can send them to jail.
Six Italian researchers and one government official have each been sentenced to six years in prison for their role in communicating ? or failing to communicate ? seismic risks in L?Aquila, Italy. That beautiful medieval town was devastated by a magnitude 6.3 earthquake in the wee hours of April 6, 2009. More than 300 people died; the aftershocks reverberated not only across Italy but also throughout the global network of seismologists.
?We?ve all been taken aback by what happened in L?Aquila,? says Thomas Jordan, a seismologist at the University of Southern California and chairman of an international commission on earthquake forecasting that was set up after the disaster.
To many, ?L?Aquila? has become a code word for scientific advice offered in good faith but hounded to injustice. The verdict drew swift condemnation from such august organizations as the American Geophysical Union. The decision ?could ultimately discourage scientists from advising governments, communicating the results of research to the public, or even in extreme cases discouraging people from working in these fields,? said AGU president Michael McPhaden.
But often lost in the outcry is the fact that the people of L?Aquila felt that they trusted science and were betrayed. This perception ? far more than the fate of any particular researcher ? is what should have all scientists deeply worried.
Central Italy is no stranger to earthquakes. The L?Aquila quake happened smack in the middle of Italy?s highest seismic risk region, where the Apennine mountains are pulling themselves apart. All through the winter and spring of 2009, residents felt the ground shake in a series of tremors. An amateur scientist started issuing predictions of future quakes based on measurements he took at a handful of radon gas detectors in the area.
Finally, the tremors got so strong that officials convened a gathering of the local risks commission. Meeting minutes show that scientists talked about how a large earthquake in L?Aquila could not be ruled out. But at a press conference held afterward, involving only two of the commission members, one of them said that the ongoing tremors helped release seismic energy in the region.
Hearing that, residents of L?Aquila felt relieved, and many decided to stay put even as the ground kept shaking. So lots of people were inside the night of April 5, and many were crushed by collapsing buildings.
Jordan says that the convicted researchers got distracted from their main job, which should have been advising the public about measures they could take to protect themselves from ground shaking. Commission members ?got snookered into answering a kind of simple yes-or-no question: ?Will we be hit by a large earthquake?? ? Jordan says. ?Seismologists can?t provide an answer to that type of question.? Instead, scientists can provide information to authorities, who must juggle various risks and decide what a particular community should do.
In L?Aquila, residents thought science could tell them what to do. It couldn?t, and so perhaps more people died than otherwise would have.
There is some good news among the bad. Jordan and his colleagues proposed some ways to improve operational earthquake forecasting, such as providing the public with openly available information about short-term seismic risks. That could be as simple as a regularly updated website, which people could get familiar with well before a big earthquake strikes. ?You don?t want to just strike up a new conversation with the public in times of seismic crisis,? Jordan says.
Another approach is to be open about earthquake risk even if scientists aren?t sure about the implications of recent seismic activity. In California not too long ago, a magnitude 4.8 quake struck near the southern San Andreas, the biggest so close to the fault in the history of seismic recording. The state earthquake evaluation council nervously released a statement that the probability of a large quake on the southern San Andreas had risen to between 1 and 5 percent per week. That quake didn?t happen, but California officials were at least prepared. All this took place in March 2009 ? two weeks before L?Aquila.
Members of the California council have statutory immunity from prosecution, which protects them from what the Italian scientists just went through. That?s one way to help fix the distrust that often lingers between the public and scientists.
Society desperately needs the information science can provide. The L?Aquila experience contains valuable lessons for both parties in how that information should be communicated.
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Apple?s Q1 2013 Breaks iPhone And iPad Sales Records With 47.8M, 22.9M Units Sold Respectively
Apple just released its earnings report for Q1 2013, ending in December of last year, with a solid hardware quarter overall. The iPhone dominated with 47.8 million units sold in the quarter, up quarterly and yearly, with Apple also breaking records with 22.9 million iPads sold. The iPhone 5 saw its first full quarter of availability this period, as well as a nice holiday sales boost. Analysts had suggested earlier this month that iPhone 5 production orders had been cut on signs of weak demand. 22.9 million iPads sold is a solid increase from last quarter’s 14 million. It’s also a 33 percent YOY increase, up from 15.4 million last year. The iPad missed predictions last quarter. Though Apple doesn’t break out specific numbers on various models, it’s fair to assume the iPad mini, which was available for the majority of the period, played a part in the increased sales along with the holiday spike. And let’s not forget, Apple also introduced an upgraded 4th-generation iPad with Lightning port alongside the little guy. However, the iPad mini has more to make up for, as its gross margin is significantly lower than other products. Apple sold 47.8 million iPhones over the three-month period, vs. 26.9 million last quarter and 37 million last year. That represents YOY growth of 23 percent. Analysts believe that the iPhone may have already saturated developed markets like the U.S. and the UK, which are Apple’s strongest regions, which explains the production cuts. However, Apple is rumored to be developing two versions of the next-gen iPhone, and one is said to be a budget model aimed at developing markets. In terms of iPods, the new family of colorful iPod products has managed to breathe a little life into a flagging business for Apple. The introduction of the iPhone has most certainly chomped into this segment of the business, but Apple still managed to sell 12.7 million, up from 5.3 million last quarter, representing a YOY loss of 18 percent.Source: http://feedproxy.google.com/~r/Techcrunch/~3/wiD2uEL6L_s/
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Wednesday, January 23, 2013
Oxygen-free energy designed to fuel brain development spurs on growth of cancer
Jan. 23, 2013 ? The metabolic process which fuels the growth of many cancers has its origins in normal brain growth finds a new study published in BioMed Central's open access journal Cancer & Metabolism. Using knock-out mice the study shows that interfering with Hexokinase-2 (Hk2), an enzyme integral to glucose metabolism, reduces the aggressiveness of medulloblastoma, the most common malignant brain tumor in children, and allows long term survival of mice.
Most cells only convert glucose to lactate in the absence of oxygen, for example, during a short burst of intensive exercise (anaerobic glycolysis). However rapidly dividing cells, including many cancer cells, convert glucose to lactate even in the presence of oxygen (aerobic glycolysis).
Researchers from the University of North Carolina have found that Hk2 switches on aerobic glycolysis in progenitor cells of the brain and in medulloblastoma. In the absence of Hk2, brain development was disordered. Additionally they found that deleting the Hk2 gene in mice genetically prone to develop medulloblastoma reduced the aggressiveness of the tumors, allowing long-term survival of the mice.
Dr. Timothy Gershon, who led this study, explained, "As long ago as 1924 Otto Warburg hypothesized that cancers use glycolysis to provide energy for growth even in the presence of oxygen. We found that glycolysis in the presence of oxygen is a developmental process that is co-opted in cancer to support malignant growth. We can now think about targeting this process in patients."
Open access publisher BioMed Central is proud to announce the launch of the Cancer & Metabolism . Professor Chi van Dang, co-Editor-in-Chief, commented that "It has become self-evident that metabolism and bioenergetics are regulated by cancer genes. Cancer & Metabolism is launched uniquely to fulfil the needs of a burgeoning field." Professor Michael Pollak, co-Editor-in-Chief, added that "The scope of Cancer & Metabolism will allow for an interdisciplinary readership including cancer biologists, endocrinologists, oncologists, clinical trialists and population scientists."
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The above story is reprinted from materials provided by BioMed Central Limited, via AlphaGalileo.
Note: Materials may be edited for content and length. For further information, please contact the source cited above.
Journal Reference:
- Timothy R Gershon, Andrew Crowther, Andrey Tikunov, Idoia Garcia, Ryan Annis, Hong Yuan, C Ryan Miller, Jeffrey Macdonald, James M Olson and Mohanish Deshmukh. Hexokinase-2-mediated aerobic glycolysis is integral to cerebellar neurogenesis and pathogenesis of medulloblastoma. Cancer & Metabolism, 2013 DOI: 10.1186/2049-3002-1-2
Note: If no author is given, the source is cited instead.
Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.
Source: http://feeds.sciencedaily.com/~r/sciencedaily/most_popular/~3/hIl6MRsTrv8/130122231353.htm
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Emotional intelligence mapped in brain: Study of Vietnam veterans with combat-related brain injuries
Jan. 22, 2013 ? A new study of 152 Vietnam veterans with combat-related brain injuries offers the first detailed map of the brain regions that contribute to emotional intelligence -- the ability to process emotional information and navigate the social world.
The study found significant overlap between general intelligence and emotional intelligence, both in terms of behavior and in the brain. Higher scores on general intelligence tests corresponded significantly with higher performance on measures of emotional intelligence, and many of the same brain regions were found to be important to both.
The study appears in the journal Social Cognitive & Affective Neuroscience.
"This was a remarkable group of patients to study, mainly because it allowed us to determine the degree to which damage to specific brain areas was related to impairment in specific aspects of general and emotional intelligence," said study leader Aron K. Barbey, a professor of neuroscience, of psychology and of speech and hearing science at the Beckman Institute for Advanced Science and Technology at the University of Illinois.
A previous study led by Barbey mapped the neural basis of general intelligence by analyzing how specific brain injuries (in a larger sample of Vietnam veterans) impaired performance on tests of fundamental cognitive processes.
In both studies, researchers pooled data from CT scans of participants' brains to produce a collective, three-dimensional map of the cerebral cortex. They divided this composite brain into 3-D units called voxels. They compared the cognitive abilities of patients with damage to a particular voxel or cluster of voxels with those of patients without injuries in those brain regions. This allowed the researchers to identify brain areas essential to specific cognitive abilities, and those that contribute significantly to general intelligence, emotional intelligence, or both.
They found that specific regions in the frontal cortex (behind the forehead) and parietal cortex (top of the brain near the back of the skull) were important to both general and emotional intelligence. The frontal cortex is known to be involved in regulating behavior. It also processes feelings of reward and plays a role in attention, planning and memory. The parietal cortex helps integrate sensory information, and contributes to bodily coordination and language processing.
"Historically, general intelligence has been thought to be distinct from social and emotional intelligence," Barbey said. The most widely used measures of human intelligence focus on tasks such as verbal reasoning or the ability to remember and efficiently manipulate information, he said.
"Intelligence, to a large extent, does depend on basic cognitive abilities, like attention and perception and memory and language," Barbey said. "But it also depends on interacting with other people. We're fundamentally social beings and our understanding not only involves basic cognitive abilities but also involves productively applying those abilities to social situations so that we can navigate the social world and understand others."
The new findings will help scientists and clinicians understand and respond to brain injuries in their patients, Barbey said, but the results also are of broader interest because they illustrate the interdependence of general and emotional intelligence in the healthy mind.
The study team also included Roberto Colom, of the Universidad Aut?noma de Madrid, and Jordan Grafman, now at the Rehabilitation Institute of Chicago.
This study was conducted in part at the Walter Reed Army Medical Center in Washington, D.C., with support from the National Institute of Neurological Disorders and Stroke at the National Institutes of Health.
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The above story is reprinted from materials provided by University of Illinois at Urbana-Champaign.
Note: Materials may be edited for content and length. For further information, please contact the source cited above.
Journal Reference:
- A. K. Barbey, R. Colom, J. Grafman. Distributed neural system for emotional intelligence revealed by lesion mapping. Social Cognitive and Affective Neuroscience, 2012; DOI: 10.1093/scan/nss124
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Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.
Source: http://feeds.sciencedaily.com/~r/sciencedaily/top_news/top_science/~3/05bjlT-1ijY/130122122306.htm
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